Sequencing preparation for drug discovery
A walkaway library preparation system with integrated quality control
An increased throughput library preparation system with high functionality and adaptability
Our library preparation system is split into pre and post-PCR workcells, both of which require one-time set-up for multiple runs.
Additionally, all deck replenishment is automated meaning there is no scientist dead time waiting for liquid handling programs to finish.
PRE-PCR
POST-PCR
On the post-PCR system there is a plate reader and fragment sizer meaning all QC can be performed as part of the sequencing preparation workflow without manual interaction.
2X Throughput increase
99% reduction in manual touchpoints
85% reduction in skilled time
This system allows operational hours to be extended, as a member of staff isn’t required for deck setups throughout the workflow.
There is temperature-controlled storage where the samples can be safely kept after the workflow has completed, ready for use when needed.
This workcell was designed around an RNA-seq protocol, and can be used to assess gene expression in response to a drug. This is particularly important in the drug discovery process to evaluate the response to a drug in a cell line or organism. This often comes after the initial high throughput screening workflows when candidates have been narrowed down.
